a convenient procedure for friedlander synthesis of quinoline derivatives catalyzed by zirconium dodecylphosphonate as an efficient and reusable catalyst
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abstract
2-amino-substituted ketones react with α-methylene ketones under solvent-free conditions at 90 °c in thepresence of a catalytic amount of zirconium dodecylphosphonate to create the corresponding quinolinesin excellent yields. this procedure recommends numerous advantages such as easy work-up, use of mild,reusable and safe catalyst, short reaction timeand high yields. the new compounds have been characterizedby 1h-nmr, 13c-nmr, mass and elemental analysis data.
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Journal title:
physical chemistry and electrochemistryجلد ۱، شماره ۴، صفحات ۱۹۵-۱۹۹
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